PTK2 and cancer: Bugide et al showed that overexpressed HPIP affects the prognosis of patients with primary breast cancer; Bugide et al studied HPIP in primary breast cancer and also found that the excessive expression caused a disproportionate prognosis and proposes to regulate HPIP‐mediated cancer cell migration by increasing the direct interaction of FAK phosphorylation of Y397 and activating FAK13.