It has been reported that miR-200c suppresses many cancer metastasis properties, for example, by inhibiting MMP-3 expression to attenuate ovarian cancer metastasis [15], downregulating E-cadherin to affect EMT in human renal cell carcinoma [16], and targeting the 3ʹUTR region of JNK2 to reduce the metastasis ability of colorectal cancer [35]. Here, MMP3 is linked to renal cell carcinoma.