EGFR and central nervous system cancer: AXL is a well‐known receptor tyrosine kinase.37 Several reports have revealed that AXL is overexpressed in human glioma and predicts poor prognosis of glioma patients.50, 51 AXL was also reported to promote glioma growth, migration, invasion, tumorigenesis and primary resistance to EGFR inhibition.37, 52, 53 The inverse expression patterns and inverse biological roles between LINC00526 and AXL implied that whether there is negative modulation between LINC00526 and AXL.