The nature of genes in which we observed stochastic allelic imbalances (i.e., V-LOH, Supplementary Data) was explored further using pathway analysis and found to be significantly enriched in pathways that define the cancerous state (Molecular Mechanisms of Cancer (Fig. 3d), mTOR signaling, Telomerase Signaling, and others, IPA analyses21, Qiagen; Supplementary Table 1). The gene discussed is MTOR; the disease is cancer.