The most common and well described virulence determinants in enterococci are aggregation substances (agg, asa1), cytolysin (cyl), gelatinase (gelE), extracellular surface protein (esp), adhesion to collagen (ace, acm), and adhesion-like endocarditis antigens (efaAfs and efaAfm) [118]. Here, CYLC1 is linked to endocarditis.