PNLIP and obesity due to melanocortin 4 receptor deficiency: Among the drugs used for the prevention of obesity and hyperlipidemia by inhibition of the pancreatic lipase activity by the Orlistat [31], from our results, the pancreatic lipase activity was inhibited by EEA by hydrolyzing of dietary triglycerides nonabsorbable into monoglycerides and free fatty acids absorbable by the intestine.