The cDNA encoding the human ß‐galactocerebrosidase enzyme was cloned and expressed in 1993.8GALC is localized on chromosome 14q31, it spreads over 58 kb and consists of 17 exons.9 The gene encodes an 80 kDa precursor protein, which is cleaved into a 50 and 30 kDa subunit.8, 10, 11 Until now, 237 mutations causing Krabbe disease have been cataloged in the Human Gene Mutation Database (professional subscription, August 2018). Here, GALC is linked to Krabbe disease.