Further differentiation of the data set into patients who died of their tumors (black dots in Fig. 6c and Supplemental Fig. S5) or patients who showed tumor progression and/or metastasis (black dots in Fig. 6d and Supplemental Fig. S5) during the observation period, revealed two patients with intermediated risk tumors, but high numbers of CD163 positive cells in the tumor microenvironment (Fig. 6c,d). The gene discussed is CD163; the disease is neoplasm.