Using high-resolution chromosome microarray analysis to screen 108 fetuses with congenital structural abnormalities, fetuses with the MECP2 duplication have been identified, presenting ventriculomegaly, hydrocephalus, agenesis of the corpus callosum, choroid plexus cysts, fetal growth restriction and hydronephrosis49. The gene discussed is MECP2; the disease is Ventriculomegaly.