MSCs are known to express receptors for several chemokines and growth factors secreted by tumor cells like platelet-derived growth factor (PDGF), interleukin 6 (IL-6), leucine-37 (LL37), prostaglandin E2 (PGE-2), and stromal cell-derived factor 1 (SDF-1). This evidence concerns the gene IL6 and neoplasm.