From the 8 genes exclusively selected by twiner (Fig. 3b), particularly 2 (SLC35E2 and UCN) have lower weights compared to the remaining genes exclusively selected by EN and selected in common by the two strategies (Table 3; Fig. 4b), corresponding to two genes that show a similar correlation pattern across AR+ TNBC and PRAD cancer types, and that are relevant in the classification of breast/prostate tissue into tumor (AR+ TNBC/PRAD) and normal tissue. This evidence concerns the gene AR and prostate adenocarcinoma.