Furthermore, Kimura et al. used a pancreatic cancer mouse model Ptf1a-Cre; KrasG12D to show that the loss of ARID1A expression promotes tumorigenesis—from PanIN to ductal adenocarcinoma (PDAC)—and enhances intraductal papillary mucinous neoplasm (IPMN) formation from the duct cell. Here, ARID1A is linked to pancreatic neoplasm.