Using VEGAS, we identified three top-ranking genes (RMND1, p = 0.000011; C6orf211, p = 0.000016; and ZBTB2, p = 0.00029) in the candidate locus (6q25.1) associated with CML. This evidence concerns the gene ZBTB2 and chronic myelogenous leukemia, BCR-ABL1 positive.