PROS1 and tuberculosis: In that respect, C-reactive protein (CRP), a non-specific inflammatory protein with POC potential for TB, has shown a high sensitivity of up to 98% albeit at a lower specificity of below 60% in the triaging for TB in symptomatic [37, 38], and a sensitivity of 89% with a specificity of 72%, respectively, in the screening of asymptomatic HIV-infected individuals [39].