We further delineate the EGR1 target genes in YYJD‐treated A549, including some apoptosis‐related genes such as KLF11,29, 30, 31 BCL2L1137, 38, 39, and DUSP6.40, 41 These observations suggest that the apoptosis of lung cancer cells induced by YYJD is possibly mediated by EGR1‐bound target genes. The gene discussed is EGR1; the disease is lung carcinoma.