In subjects with active TB, the Ka between monocytes and CD4+CD8+ (DPOS) T cells or CD4+ T cells was significantly higher than for CD8+ T cells (Figure 4F) and both DPOS and CD4+ T cell:monocyte complexes had higher Ka in active TB compared to dengue hemorrhagic fever (Figure 4—figure supplement 3). Here, CD4 is linked to Dengue hemorrhagic fever.