Therefore we used several cancer cell lines with high CEA expression, which include colorectal cancer HT‐29, pancreatic cancer AsPC‐1, and gastric cancer MGC803 cells, and tested the strong anti‐tumor activity of CEA‐CAR‐T cells in combination with rhIL‐12 against these cancer cell lines. Here, CEACAM5 is linked to familial pancreatic carcinoma.