The model includes important features such as tumor growth, detailed representation of the antigen processing and presentation by mature antigen presenting cells (mAPC), migration of the mAPC to tumor-draining lymph node(s) (TdLN), T cell priming, egress and distribution of effector T cells (Teff) to the tumor and the rest of the body, PD-1/PD-L1 axis between Teff and cancer cells, as well as inhibitory mechanisms through regulatory T cells (Treg). This evidence concerns the gene CD274 and cancer.