PLA2G7 and ischemic stroke: Although Lp-PLA2 activity correlates with Lp-PLA2 mass [4], the risk of ischemic stroke with Lp-PLA2 activity and mass is inconsistent; for example, a meta-analysis of individual patient data (IPD) demonstrated that higher Lp-PLA2 mass, but not activity, may increase ischemic stroke risk [5].