Using platforms such as microarrays, whole genome sequencing, targeted deep sequencing, and SNP arrays, several important pathways such as ErbB-PI3K, Akt-mTOR, Notch, and NF-κB were found to be frequently altered among NPC patients [10–12], suggesting that these pathways could be targeted for treating NPC. Here, NFKB1 is linked to nasopharyngeal carcinoma.