NPPB and heart failure: In line with this, we found no differences in heart or lung weight or the expression of cardiac signature molecules of heart failure, ANP and BNP (encoding atrial and brain natriuretic peptides, respectively), pathological remodeling (increased myosin heavy chain β/α ratio, encoded by MYH7 and MYH6, respectively) and hypertrophy (ACTA1 encoding α-skeletal actin) (Table S2).