Lack of statistically significant correlations were found between the levels of VDR (with one exception described above), CYP27B1, CYP24A1 and ROR, and histopathological diagnosis of uveal melanoma (spindle-cell melanoma, mixed and epithelioid cell-type), the degree of sclera infiltration, the degree of optic disc infiltration, the presence of tumor cell emboli in the scleral vessels, the involvement of the ciliary body, tumor size (the largest base diameter and height), tumor shape (mushroom-shaped, dome-shaped and diffuse), the clinical advancement stage (AJCC) and 2-year survival. The gene discussed is VDR; the disease is uveal melanoma.