EMB and neoplasm: To evaluate efficacy in a therapeutic CT26 lung metastasis model (Fig. 6a), LADD and Lm-RIID were engineered to express the T cell epitope AH1-A5 from the tumor rejection antigen gp70 (33, 34) fused to ovalbumin (OVA) (LADD-AH1-A5-OVA and Lm-RIID-AH1-A5-OVA).