The clinical characteristics of the NTUH AML patients were listed in Additional file 1: Table S1 Patients with higher HOXB-AS3 expression were older and had higher frequencies of mutated NPM1/wild FLT3-ITD, MLL-PTD, and RUNX1 mutations, but lower frequency of CEBPAɑ double mutations than patients with lower expression. Here, RUNX1 is linked to acute myeloid leukemia.