Based on the assumptions that there is a connection between STAT3 and EMT and/or angiogenesis signaling pathways in GC, this study aimed to investigate the possible relations between immunohistochemical expression of STAT3 and adhesive molecules (E-cadherin and β-catenin) and angiogenesis-related factors (VEGF, HIF1α and MVD). The gene discussed is VEGFA; the disease is gastric cancer.