Several marine secondary metabolites with anti-obesity properties have already been reported, such as the 5-alkylpyrrole-2-carboxaldehyde derivatives, isolated from the sponge Mycale lissochela, which have protein-tyrosine phosphatase 1B (a recognized target for obesity) inhibitory activity [6]. The gene discussed is PTPN1; the disease is obesity due to melanocortin 4 receptor deficiency.