IL10 and neoplasm: B lymphocyte subtypes B10 and Breg, tumor-associated macrophages (TAMs), and myeloid-derived suppressor cells (MDSCs) produce immunosuppressive factors such as interleukin 10 (IL-10) and interleukin 12 (IL-12), which are used by malignant cells to hide from immunosurveillance [37,38].