A comparison of biodistribution and tumor targeting properties between [125I]I-PIB-(HE)3-G3 and [125I]I-(HE)3-G3 was performed in BALB/C nu/nu mice, bearing HER2-expressing SKOV3 xenografts, at 3 and 6 h post-injection (pi) (Figure 3). This evidence concerns the gene ERBB2 and neoplasm.