Sasaki et al. [16] applied a Dako EnVisionTMFLEX detection system with the VE1 antibody and compared these findings with the results of direct sequencing in Japanese lung ADC, demonstrating that the autostainer IHC VE1 assay exhibited excellent sensitivity (100%) in 5 of 5 BRAF V600E-mutated tumors and specificity (95.2%) in 20 of 21 BRAF non-V600E tumors. This evidence concerns the gene BRAF and AIDS dementia complex.