Moreover, in OCI/AML3 leukemia cells, where mutant NPM1 is localized in the cytoplasm [66], it has been demonstrated that typically nuclear FOXM1 is predominantly co-localized with NPM1 in the cytoplasm, while NPM1 knockdown leads to the disappearance of FOXM1 from the cytoplasm, suggesting that NPM1 may also determine intracellular localization of FOXM1 [67]. The gene discussed is NPM1; the disease is leukemia.