Moreover, the addition of the FOXM1 inhibitor thiostrepton (TST) to FLT3-ITD positive and negative AML cells was able to induce the apoptosis of MV4–11 and THP1 in a dose-dependent manner, concluding that FOXM1 may be useful as potential prognostic marker and therapeutic target in AML [48]. This evidence concerns the gene FLT3 and acute myeloid leukemia.