The intracellular accumulation of bodipy FL prazosin was markedly reduced not only in BCRP-overexpressing YD-9/CIS, but also in YD-8/CIS and YD-38/CIS cells compared to parental cells, suggesting that prazosin is also transported by MDR1 [29,30]. This evidence concerns the gene ABCB1 and in situ carcinoma.