Within the cohort of ICU patients, plasma concentrations of CTRP3 were significantly decreased in patients with sepsis (n = 145, median 493.4 ng/mL, range 82.9–2395.3 ng/mL) as compared to patients without sepsis (n = 73, median 758.8 ng/mL, range 260.4–2269.1 ng/mL, p < 0.001; Figure 1a). Here, C1QTNF3 is linked to Sepsis.