Celiac disease is strongly associated with Human Leukocyte Antigen (HLA) and approximately 95% of CeD patients express HLA-DQ2 encoded by DQA1*05 and DQB1*02 and the rest 5% carry DQ8 alleles encoded by DQA1*03 and DQB1*0302 alleles [47]. The gene discussed is HLA-DQA1; the disease is cranioectodermal dysplasia.