AGTR1 and myocardial infarction: Post myocardial infarction (MI), both circulating pro-inflammatory cytokines (PICs) and plasma angiotensin II (Ang II) increase [11,18] and can contribute to upregulation of Ang II-AT1R signaling and cytokines in the paraventricular nucleus (PVN) of the hypothalamus [14,15,17,19].