On the other hand, a large scale expression profiling of RECQL5 in human breast cancer showed that high expression of the helicase is often associated with bad tumor grades and poor prognosis.38 In line with that, our analysis of RECQL5 expression data also suggests that higher levels of expression are correlated with poorer prognosis of TNBC patients (Figure 5E). This evidence concerns the gene RECQL5 and breast carcinoma.