In a systemic lupus erythematosus (SLE) Korean cohort with 781 patients, a hybrid approach with a GWAS array and Immunochip genotyping allowed for the sensitive detection of two SLE risk loci, XKR6 and GLT1D1, which were found to be significantly higher in childhood-onset SLE (19). This evidence concerns the gene GLT1D1 and systemic lupus erythematosus.