Infection of respiratory epithelial cells with influenza virus is reported to stimulate PLD activity and chemical inhibitors of PLD2, RNAi depletion of PLD2 and pre-treatment with primary alcohols have all been reported to decrease the number of cells infected with viral particles and also the viral titer produced post-infection (O’Reilly et al., 2014; Oguin et al., 2014). This evidence concerns the gene GPLD1 and infection.