Oral administration of L. plantarum KTCT3104, L. curvatus KTCT3767, and Lactobacillus reuteri ATCC23272 was shown to alleviate allergic asthma by inhibiting AHR and reducing the production of Th2 cytokines, such as IL-4 and IL-5 in BAL fluids (13, 39). The gene discussed is IL5; the disease is allergic asthma.