LGALS9 and abortion: Recently, lower levels of Lgals9 expression analyzed by immunohistochemistry were described in trophoblasts of the DBA/2-mated CBA/J mouse model of spontaneous abortion/PE when compared to normal CBA/J × BALB/c matings, further showing that Lgals9 blockade promoted a significant imbalance of Th1/Th2 immunity in this model (150).