Control of splenomegaly was linked with the marker D4Mit23 (corrected P = 0.0426, 4.76% of variance explained), skin lesion size (kinetics of development of skin lesions)—with D4Mit172 and D4Mit23 (corrected P = 0.00201 and 0.0226, respectively), level of IFNγ in serum—with D4Mit53 (corrected P = 0.000692, 8.08% of variance explained), and level of IL-4 in serum—with D4Mit53 (corrected P = 0.0132, 5.72% of variance explained). The gene discussed is IFNG; the disease is Splenomegaly.