Furthermore, we found that volunteers with hypocortisolemia (n = 31; μ = 10229.54 ± 506.92 pg/mL; 95% CI: 8992.79–11606.33) showed lower levels of baseline serum BDNF when compared to volunteers with eucortisolemia (n = 38; μ = 12574.61 ± 680.59 pg/mL; 95% CI: 11394.32–13754.91) (Independent Student T-test: t = −2,468, df = 67, p = 0.016) (Figure 3A). The gene discussed is BDNF; the disease is adrenocortical insufficiency.