PTGES and cancer: Genetic deletion as well as pharmacological inhibition of mPGES-1 have demonstrated this target as an effective anti-cancer regimen (Hanaka et al., 2009; Kamei et al., 2009; Nakanishi et al., 2011; Sasaki et al., 2012; Howe et al., 2013; Takahashi et al., 2014; Zelenay et al., 2015; Kock et al., 2018).