SLC11A2 and hereditary hemochromatosis: Interestingly, 59Fe-NTBI uptake was impaired in ZIP14/SLC39A14 null mice when fed with iron-loaded diet or crossed with mouse models of hereditary hemochromatosis, while DMT1 siRNA reduced iron loading in a mouse model of hereditary hemochromatosis (Wang et al., 2019), thus highlighting the role of both NTBI transporters in the complex homeostasis of iron overload, with cerebral implications.