Ingrassia et al. (2017) have recently shown an altered pattern of iron transporters with iron overload in patients’ fibroblasts with WDR45 mutations, a NBIA gene with a predicted role in autophagy (Hayflick et al., 2013). PLA2G6 knockout mice (Beck et al., 2015) and fibroblasts of a patient with Neuroferritinopathy (Barbeito et al., 2010) also showed altered expression of iron transporters with DMT1 up-regulation. The gene discussed is SLC11A2; the disease is neurodegeneration with brain iron accumulation.