IL6 and amyotrophic lateral sclerosis: There was no difference in plasma IL-6 levels between controls and ALS patients (p = 0.3614) and there was no correlation between IL-6 levels in plasma and ADEs (r = 0.3384, p = 0.2173 for ALS group; r = −0.2657, p = 0.4038 for control group; Supplementary Figures S3B,C).