Arginine vasopressin is essential for both osmotic and cardiovascular homeostasis and exerts important physiological regulation through 3 receptors, V1a, V1b, and V2.46 Results of animal study showed that the V1a receptor has an important role in normal resting arterial BP regulation mainly by regulating circulating blood volume and through baroreflex sensitivity.46 Arginine vasopressin has also been previously associated with congestive heart failure.47 This evidence concerns the gene AVP and congestive heart failure.