AKT1 and neoplasm: Western blotting analysis from representative tumour tissues demonstrated that deoxyshikonin decreased PI3K, p-PI3K, Akt, p-Akt308 and mTOR proteins expression, which were consistent with the in vitro results (Figure 7(C)) (*p < 0.05, **p < 0.001, ***p < 0.0001 versus control (0 μg/mL)).