Our finding that high circulating concentrations of the VP marker copeptin was linked to higher occurrence of NAFLD is in line with our previous findings that obese rats with water induced reduction of VP concentration have a lower risk of liver steatosis compared with control rats [14] and that obese patients with biopsy-proven NAFLD had significantly higher copeptin concentrations than both obese patients without NAFLD and nonobese individuals [24]. The gene discussed is AVP; the disease is fatty liver disease.