ITGAM and viral infectious disease: Given our earlier data above demonstrating that CD11b+ myeloid cells represented the bulk of the lung-infiltrating cell population in Park2−/− mice at day 3 after viral infection (Figures 2C and 3C) and the essential role of myeloid lineage cells in initiating antiviral inflammation (Varol et al., 2015), we next investigated the effect of Parkin on the production of virus-induced inflammatory cytokines in BMDCs.