Nine of the genes for nemaline myopathy encode proteins of the sarcomere, in addition, MYO18B is also a sarcomeric protein localized to the Z lines (Ajima et al. 2008) and may yet prove to be a causative gene of nemaline myopathy, although the phenotype of affected patients is different from others reported. This evidence concerns the gene MYO18B and nemaline myopathy.