A GWAS in Taiwanese Han Chinese identified two novel migraine susceptibility SNPs: rs655484 in DLG2, a gene involved in glutamatergic neurotransmission; and rs3781545 in GFRA1, which encodes a receptor for glial cell line-derived neurotrophic factor (GDNF) in trigeminal neurons [243]. Here, GDNF is linked to migraine disorder.